Adaptive Trial Designs

Adaptive Design Development and Implementation

Innovation + Adaptive Trial Design = Paradigm Shift

Adaptive Trial Design is all about adapting and evolving your strategies to match your data. It isn’t the answer for all clinical trials, but it holds much promise for the future of clinical trials. Quintiles has designed and/or implemented Adaptive Trial Designs for indications in: oncology, cardiovascular, endocrinology, CNS and women’s health.

Potential benefits of Adaptive Design Development include:

  • Shorter timelines
  • Increased compound’s associated expected NPV (Net Present Value)
  • Decreased costs
  • Increased chance of a trial being positive and meeting the efficacy criteria for NDA approval

The FDA’s “Critical Path Opportunities List” calls for the greater use of Adaptive Trial Designs