Drug Discovery and Metabolism
In Vitro ADME and Metabolite Identification
Advion Bioanalytical Labs also offers drug discovery, in vitro ADME and metabolite identification services. Our Indianapolis, IN-based lab utilizes HPLC, MS/MS, radioprofiling, PCR and in vitro technologies to deliver a range of pre-clinical services:
- In Vitro Discovery Services
- Precipitation/solubility screening
- Metabolite stability
- CYP inhibition and induction
- Permeability assays
- Time dependent inhibition
- Clearance evaluation
- Reaction phenotyping
- Metabolism Services
- Metabolite fingerprinting
- Metabolite profiling
- In vitro and in vivo metabolism identification
- Radioprofiling
- Discovery Bioanalytical Services
- High throughput bioanalytical
- Blood-brain barrier transport analysis
Our 22,000 s.f. Drug Discovery and Metabolism Center of Excellence includes:
- Seven wet laboratories
- Orbitrap, triple quadrapole, time-of-flight, and ion trap mass spectrometry equipment
- Automated in vitro sample preparation and handling equipment
- Radioprofiling capabilities
We employ best practices to ensure scientific integrity that sets the bar within the industry. For specific details of our record please contact clinical@quintiles.com.
