- Quintiles-drkoop.com Clinical Trials Information Center expands awareness and availability of clinical trials as a treatment option for consumers
- Service harnesses power of the Internet to accelerate enrollment of qualified patients, increasing speed and efficiency of drug development process
- Center is first consumer on-line service with interactive pre-screening, enrollment tracking features

BALTIMORE, MD - June 28, 1999 - drkoop.com (Nasdaq: KOOP) and Quintiles Transnational Corp. (Nasdaq: QTRN) today announced the launch of the first interactive, consumer Internet resource to enable interested individuals to sign up on-line for possible participation in clinical drug trials via the www.drkoop.com Web site.

The Quintiles-drkoop.com Clinical Trials Information Center is a joint effort of drkoop.com, a leading Internet healthcare Web site, and Quintiles, the world's leading provider of healthcare services to the pharmaceutical industry and largest clinical trials management organization.

The center will give drkoop.com's 1.5 million monthly visitors access to information about clinical trials under way to test new investigational drugs in oncology, women's health and other therapeutic areas. It also will feature advanced on-line pre-screening to help identify the best candidates for further evaluation by physicians conducting the trials, increasing the efficiency and speed of the clinical trials process.

"Patient enrollment is the No. 1 challenge in completing clinical trials on a timely basis," said Dennis Gillings, Ph.D., Chairman and Chief Executive Officer of Quintiles Transnational Corp. "I believe the Quintiles-drkoop.com Clinical Trials Information Center will help meet this challenge while giving individuals expanded options to manage their healthcare. This new service, one of many Quintiles initiatives to harness the power of the Internet in product development and commercialization, reflects the strengths of both our organizations to give consumers greater control over their own healthcare."

Dr. C. Everett Koop, Chairman and founder of drkoop.com, said: "Today, only a small percentage of consumers are aware of clinical trials as a healthcare option, both from the standpoint of receiving a high level of care and in helping develop the latest products to treat debilitating or life-threatening diseases. Working with Quintiles, we can greatly expand awareness of this treatment option and give consumers the power to participate in studies that could benefit them individually and advance healthcare worldwide."

The Center offers access to information about a number of ongoing studies, including a summary of the trial, inclusion and exclusion criteria, and contact information for the closest or most appropriate clinical site. Neither the trial sponsor nor investigative drug being studied are identified.

In a few weeks, interactive questionnaires to pre-screen potential participants will be added to the Clinical Trials Information Center. An individual's responses will be evaluated to determine if they meet the trial's basic criteria. If the criteria are met, the individual will be given information immediately about the most appropriate clinical site to contact. No information is stored or transferred without the individual's consent during this process. The final decision to participate requires evaluation and approval by the physician investigator and the patient's informed consent.

Unique to the Quintiles-drkoop.com Center, interactive pre-screening should increase the likelihood that patients referred to a site are qualified to participate in the trial.

Interested individuals who do not fit a trial's inclusion criteria will receive other useful information, and can consent to have their pre-screening information stored in a database and matched with appropriate trials in the future. To protect privacy, personally identifiable information will be disclosed only to an investigator site, only with an individual's permission and only to help them participate in a clinical trial. Individuals may withdraw their consent from participation in the program and require that their personal information be removed from the database at any time.

The Clinical Trials Information Center also includes current information about the role of clinical trials in drug development, patient rights issues and other educational materials.

About Quintiles

Quintiles Transnational Corp. is the market leader in providing a full range of integrated product development and commercialization solutions to the pharmaceutical, biotechnology and medical device industries. Quintiles also is a leader in the electronic data interchange and healthcare informatics industry and provides healthcare policy consulting to governments and other organizations worldwide.

Headquartered near Research Triangle Park, North Carolina, Quintiles is a Forbes Platinum 400 and Fortune 1000 company and a member of the Nasdaq-100 Index. With more than 18,000 employees worldwide and offices in 31 countries, Quintiles operates through specialized work groups dedicated to meeting customers' individual needs. Visit the Quintiles Transnational Web site at www.quintiles.com.

Information in this press release contains "forward-looking statements." These statements involve risks and uncertainties that could cause actual results to differ materially, including without limitation, the risks that new products and features will not gain market acceptance, that revenues associated with new products and features will not be sufficient to offset costs or maintain the company's growth rate, actual operating performance, the ability to operate successfully in new lines of business and the ability to maintain large client contracts or to enter into new contracts. Additional factors that could cause actual results to differ materially are discussed in the company's recent filings with the Securities and Exchange Commission, including but not limited to its S-3 and S-4 Registration Statements, its Annual Report on Form 10-K, its Form 8-Ks, and its other periodic reports, including Form 10-Qs.

About drkoop.com, Inc.

The Company operates www.drkoop.com, a leading Internet-based consumer healthcare network. The Network consists of a consumer-focused interactive Web site that provides users with comprehensive healthcare information and services, as well as affiliate relationships with portals, other Web sites, healthcare organizations and traditional media outlets. The drkoop.com Network is an Internet healthcare initiative that integrates dynamic healthcare content on a wide variety of subjects, interactive communities and tools as well as opportunities to purchase healthcare-related products and services online. drkoop.com is the exclusive provider of health and related content on three Web sites of the GO Network: GO Health Center, ESPN.com Training Room and the Family.com Health Channel. drkoop.com is also the premier health content provider for GO's ABCNEWS.com. Additional information on drkoop.com can be found at www.healthcentral.com.

This news release includes forward-looking statements that are based on current expectations and involve risks and uncertainties. drkoop.com cannot guarantee that actual future events will not vary materially from those described in this release. Specifically, the actual deployment of the new Web site features described above is subject to revision due to technical and other factors and this new feature may not be accepted by consumers. For a further discussion of the business risks faced by drkoop.com, please see the section captioned "Risk Factors'' in our Registration Statement on Form S-1 filed with the Securities and Exchange Commission. drkoop.com undertakes no obligation to update any of the forward-looking statements in this release.

"Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: Statements in this press release regarding drkoop.com, Inc.'s and Quintiles' businesses which are not historical facts are "forward-looking statements" that involve risks and uncertainties. For a discussion of such risks and uncertainties, which could cause actual results to differ from those contained in the forward-looking statements, see "Risk Factors" in Quintiles' Annual Report or Form 10-K for the fiscal year ended Dec. 31, 1998, and drkoop.com's final prospectus filed June 8, 1999.