RESEARCH TRIANGLE PARK, N.C. - October 15, 2001 - Quintiles Transnational Corp. (Nasdaq: QTRN) announces the following physician appointments in clinical development:

Oren J. Cohen, M.D., to Director, Medical and Scientific Services, division of Clinical Development Services. Dr. Cohen provides direction and medical expertise in clinical trials involving infectious diseases with an emphasis in virology and HIV disease. Dr. Cohen holds an academic appointment as Clinical Associate Professor of Medicine at the George Washington University School of Medicine in Washington, D.C., and is also a Fellow of the Infectious Diseases Society of America. Dr. Cohen is based in Rockville, Maryland.

Dr. Cohen joins Quintiles from the National Institute of Allergy and Infectious Diseases (NIAID), where he served over 10 years in multiple positions, most recently as Assistant Director of Medical Affairs and as the Executive Secretary, Department of Health and Human Services/Henry J. Kaiser Family Foundation Panel on Clinical Practices for the Treatment of HIV Infection. Before that, Dr. Cohen served as Medical Officer and Clinical Associate in the NIAID Laboratory of Immunoregulation. Dr. Cohen brings extensive research experience and a strong clinical background to Quintiles.

Dr. Cohen received his medical degree from Duke University School of Medicine, and completed his residency at the New York Hospital, Cornell University Medical Center. He completed a fellowship at the NIAID. Dr. Cohen is Board Certified in Infectious Diseases.

Ross M. Tonkens, M.D., to Director, Medical and Scientific Services, in the division of Clinical Development Services, specializing in cardiovascular, respiratory, and critical care. Dr. Tonkens will be responsible for providing medical expertise for clinical trials with emphasis on cardiovascular drug and device development. Dr. Tonkens is based in Durham, North Carolina.

Dr. Tonkens joins Quintiles after more than 20 years as an internist and cardiologist in private practice in Nevada and California. In addition to his clinical experience, Dr. Tonkens has held several administrative and leadership positions for managed care organizations, most recently serving as medical director and primary clinical investigator for Lovelace Scientific Resources in Las Vegas.

Dr. Tonkens received his medical degree from Yale University School of Medicine. He completed his internship in general and cardiac surgery, his residency in internal medicine, and a fellowship in clinical cardiology at Cedars-Sinai Medical Center in Los Angeles. Dr. Tonkens is Board Certified in Internal Medicine.

Claude L. Hughes, M.D., Ph.D., to Director, Medical and Scientific Services, in the division of Clinical Development Services, focusing on clinical trials involving women's health issues.

Dr. Hughes joins Quintiles from the Avalon Medical Group in Chapel Hill, N.C., where he was in private practice specializing in women's health, specifically reproductive endocrinology, menopause and infertility. Prior to private practice in Chapel Hill, Dr. Hughes served as a professor of Obstetrics and Gynecology at the University of California Los Angeles School of Medicine at Cedar-Sinai Medical Center, Los Angeles, where he also held the Women's Guild Endowed Chair in Women's Health as well as served as the director of the Center for Women's Health. Earlier, Dr. Hughes held faculty positions at both Duke University Medical Center in Durham, N.C. and Wake Forest University School of Medicine in Winston-Salem, N.C. Dr. Hughes has also served as a principal investigator on numerous clinical trials during his medical career. Dr. Hughes will continue his academic affiliation as a Consulting Professor in the department of Obstetrics and Gynecology at Duke University Medical Center.

Dr. Hughes received his medical degree from Duke University School of Medicine, and completed his residency and fellowship in Reproductive Endocrinology and Infertility as well as a Ph.D. in Anatomy also from Duke. Dr. Hughes is Board Certified in Obstetrics & Gynecology as well as Reproductive Endocrinology. Dr. Hughes is based in Durham, North Carolina.

David C. Frakes, M.D., F.R.C.P.(C), Vice President, Medical and Scientific Services, said: "The appointments of Drs. Cohen, Tonkens and Hughes build upon Quintiles' strong medical and scientific foundation, and further strengthen the diversity of our therapeutic capabilities. Our customers benefit from the range and depth of our medical resources that add important expertise in the development of new medicines for patients. In addition, our physicians provide medical knowledge in assessing new opportunities for discovery and investment through Quintiles' PharmaBio Development group."

Quintiles' clinical development unit offers global expertise in drug development from Phase II through regulatory submission and consists of services including clinical trials management, investigator recruitment, patient recruitment, study monitoring, and data management and biostatistical services. At any one time, Quintiles is involved in approximately 1,000 clinical trials worldwide.

Quintiles Transnational is the world's leading provider of information, technology and services to bring new medicines to patients faster and improve healthcare. Headquartered near Research Triangle Park, North Carolina, Quintiles employs a global workforce and is a member of the S&P 500 and Fortune 1000. For more information visit the company's Web site at