With up to 70 percent of all trials experiencing enrollment delays, nearly half completing later than originally planned, and one-fifth of sites recruiting no patients, it’s clear that a new approach to study start-up is required. To reduce delays that negatively impact trial execution and future revenue, a more holistic, comprehensive method is emerging. Quintiles has created the Right Start approach – a study start-up solution that incorporates protocol validation, feasibility and planning, site selection and contracting, regulatory/ethics submissions, document management, and patient recruitment as an integrated process. Our framework of tools, processes and expertise is reducing timelines and improving the chance of trial execution success.