RESEARCH TRIANGLE PARK, N.C. - October 15, 1998 - Quintiles Transnational Corp. (Nasdaq: QTRN) today announced the opening of an office in Sao Paulo, Brazil, further expanding the company's ability to serve pharmaceutical customers in Latin America and globally.

Based in the world's sixth-largest pharmaceutical market, Quintiles Brazil already is working on four global trials in cooperation with Quintiles' regional staff of 30 based in Buenos Aires, Argentina, and home-based clinical monitors in Chile. Quintiles Latin America now has a total staff of 60, with offices in Mexico City, Buenos Aires and Sao Paulo and home-based monitors in Santiago, Chile, and Caracas, Venezuela.

"Quintiles Brazil adds significantly to our ability to conduct harmonized, world-class clinical research in Latin America and also as part of a global project," said Jim Ogle, President and Chief Operating Officer of Quintiles Contract Research Organization (CRO) service group. "Quintiles' specialized knowledge and advanced technology allow us to accelerate development of our customers' products locally, regionally or globally. Our customers benefit from this 'worldwide, next door' approach to service."

The Brazil office, with seven employees, is headed by Charles Schmidt, M.D., Ph.D., who reports to Alcides Cupido, M.D., Managing Director, Quintiles Latin America Inc. The address is Av. Angalica, 819-6 andar Cj.61/62, CEP 01227-000, Sao Paulo, Brazil. Telephone: +55 11 826-8680 or +55 11 826-8625. Fax: +55 11 36 62 25 66.

Quintiles Transnational Corp. is the market leader in providing a full range of integrated product development and marketing services to the pharmaceutical, biotechnology and medical device industries. Quintiles also provides healthcare policy consulting and health information management services to healthcare and governmental organizations worldwide. Quintiles is headquartered near Research Triangle Park, North Carolina. With more than 14,000 employees worldwide and offices in 30 countries, Quintiles operates through specialized work groups dedicated to meeting customers' individual needs. Visit our web site at www.quintiles.com.