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  • Therapeutic Expertise Translational Oncology

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  • Quintiles Clinical Trial

    With the complexity of oncology clinical trials, how can you succeed – or fail – faster? 

    Translational research helps you understand a compound’s biology, critical for developing targeted therapies. Quintiles’ Translational R&D Center for Excellence provides scientific insight into targets, molecular signaling and clinical outcomes.

    Our translational research capabilities include:

    • Performing compound mechanism-of-action (MOA) studies and pathway elucidation 
    • Identifying predictive and pharmacodynamic biomarkers
    • Developing and validating genomic and proteomic assays that focus on pathways and biomarkers for the drug and tumor type
    • Whole genome deep sequencing
    • In vivo TumorGraft testing
    • Microarray SNPs (single nucleotide polymorphism)
    • Recommending drug combinations to improve clinical outcome and/or preemptively overcome mechanisms of resistance
    • Identifying potential target patients and tumor types
    • Assessing cardiotoxicity of compounds early in development
    • Offering integrated genomics solutions to identify biomarkers for evaluating drug efficacy, toxicity and responsiveness

  • Quintiles Clinical Trails

    Quintiles can help you map stakeholder requirements and integrate these into the development process from the very beginning, incorporating critical endpoints to drive more efficient clinical trials. Watch Video

  • Quintiles Clinical Trails

    Prospective identification and potential amelioration of cardiotoxicity is a critical component of contemporary drug development. 
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